Novel chemical structure
The chemical structure of YUPELRI is a novel biphenyl carbamate tertiary amine structure that is distinct, making it the first inhaled LAMA of its class for COPD.
When administered, YUPELRI exhibits pharmacological effects through inhibition of M3 receptors at the smooth muscle leading to bronchodilation.1
For illustrative purposes only. Elapsed animation does not represent actual response time.
An exploratory analysis of the time to achieve a 100 mL increase in FEV1 on day 1 showed that the median (95% CI) time to achieve an increase in FEV1 of 100 mL was 30 minutes in Study 1 (30 to 60 minutes) and Study 2 (30 to 90 minutes).